Confirming Cerebral Malaria Deaths in Resource-Limited Settings

Confirming Cerebral Malaria Deaths in Resource-Limited Settings

A 4-year-old Papua New Guinean girl presented with unresponsive coma (Blantyre coma score = 2) after a short febrile illness. She did not have neck stiffness, a positive Kernig’s sign, or other clinical features of bacterial meningitis. Microscopy confirmed a peripheral blood Plasmodium falciparum asexual parasite density of 33,960/mL. Despite parenteral artemether and intensive supportive ther...

Management of severe paediatric malaria in resource-limited settings

Over 90% of the world's severe and fatal Plasmodium falciparum malaria is estimated to affect young children in sub-Sahara Africa, where it remains a common cause of hospital admission and inpatient mortality. Few children will ever be managed on high dependency or intensive care units and, therefore, rely on simple supportive treatments and parenteral anti-malarials. There has been some progre...

Resuscitation in resource-limited settings.

Intrapartum-related hypoxia leading to deaths and disabilities continues to be a global challenge, especially in resource-limited settings. Primary prevention during labour is likely to have a significant impact, but secondary prevention with focus on immediate basic stabilization at birth can effectively reduce a large proportion of these adverse outcomes as demonstrated in the resource-rich s...

Viral load testing in resource-limited settings.

Establishing Medical Schools in Limited Resource Settings

INTRODUCTION One urgent goal of countries in sub-Saharan Africa is to dynamically scale up the education and work force of medical doctors in the training institutions and health facilities, respectively. These countries face challenges related to the rapid scale up which is mostly done without proper strategic planning, without the basic elements of infrastructure development, educational as w...